Genomics

The 100,000 Genomes Project aims to bring the benefits of personalised medicine to the NHS. To make sure patients benefit from innovations in genomics, the Government has committed to sequencing 100,000 whole human genomes, from 70,000 patients, by the end of 2018.

Successful delivery of the 100,000 Genome Project will enable us to achieve a number of ambitions, including:

  • to increase understanding of genetic variants leading to new treatments and diagnostics
  • to accelerate the uptake of advanced genomic medicine integrated into the NHS
  • to promote greater public understanding of the benefits of genomic medicine
  • to stimulate the UK life sciences industry and commercial activity in genomics

The role of NHS England is to prepare the NHS to harness the power of genomic technology and science to improve the health of our population.  The NHS will be the world-leading healthcare system in its use of cutting edge genomic technologies to predict and diagnose inherited and acquired disease, and to personalise treatments and interventions. The NHS will also be able to support a greater understanding of disease and its evolution, building new strategic partnerships with Research and Development and Industry for the benefit of patients and the public in this country and beyond.

The UK is recognised worldwide as a leader in genomics and the unique structure of the NHS is allowing us to deliver these advances at scale and pace for patient benefit. To maintain this we know that there is a need to continue this life changing work when the 100,000 Genomes Project concludes at the end of 2018. With this in mind, the NHS England Board has approved the establishment of a national NHS Genomic Medicine Service providing comprehensive and equitable access to the latest in genomic testing and management for the whole country, regardless of condition and where people live.

The 100,000 Genomes Project is cementing the NHS’s position as one of the most advanced healthcare systems in the world, and is providing the foundation for a new era of personalised medicine, and this in turn will contribute towards delivering high quality care for all, now and for future generations.

Genomics Medicine Centres

NHS England has established 13 NHS Genomics Medicine Centres (GMC) to cover the country delivering an end-to-end genomic medicine pathway. They are enabling the participation of patients and family members with their informed consent; collecting samples to extract DNA; capturing clinical information to inform the interpretation of the genome sequence; and establishing the infrastructure to make genomic medicine a routine part of NHS care.

All NHS GMCs work to a highly detailed, and constantly updated, service specification set by NHS England, which at its core is about delivering to high quality standards and establishing an infrastructure to support personalised medicine. This common approach ensures consistency and coherence across the NHS to gain maximum benefits from this application of genomic technologies and curation of knowledge, and is laying the foundations for the future.

The UK is recognised worldwide as a leader in genomics and the unique structure of the NHS is allowing us to deliver these advances at scale and pace for patient benefit.

The 100,000 Genomes Project is cementing the NHS’s position as one of the most advanced healthcare systems in the world, and is providing the foundation for a new era of personalised medicine, and this in turn will contribute towards delivering high quality care for all, now and for future generations.

Find out more

Image of the front cover of the report '100K Genomes Project Paving the Way to Personalised Medicine'100K Genomes Project – Paving the Way to Personalised Medicine

 

 

 

 

 

For further information about the 100,000 Genomes Project, please see the Genomics England website. To find out details on genomics education and training for NHS staff, please see the relevant section of the Heath Education England website.

If you have any queries regarding any aspect of the 100,000 Genome Project please contact the Genomics Central Coordinating Team Genomics Implementation Unit at NHS England by email: england.genomics@nhs.net.