Evidence based venous thromboprophylaxis in patients undergoing total hip replacement (THR), total knee replacement (TKR) and hip fracture surgery (HFS)

Venous thromboprophylaxis comprises mechanical and pharmacological intervention but for added protection in major orthopaedic surgery, most national and international guidelines advise a combined regimen of both modalities. They recommended that pharmacological prophylaxis is timely initiated postoperatively. Extended pharmacological prophylaxis is recommended for 28–35 days for hip replacement and hip fracture surgery and 10–14 days for knee replacement surgery.