This report provides the following information about the provision and commissioning of highly specialised services during 2020/21:

• a description of each service
• a list of the expert centres that deliver the service
• NHS England’s expenditure on each service
• a measure of the activity that each service undertakes (patient numbers fewer than 30 are not included because of the risk of identifying individual patients)
• clinical outcomes from the service
• information about geographical equity in access to the service
• an update on new highly specialised services.

Appendix B summarises NHS England’s commissioning arrangements for highly specialised services across the devolved nations.