Interim clinical commissioning policy: Remdesivir and molnupiravir for non-hospitalised patients with COVID-19

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This policy specifically outlines the treatment options for remdesivir and molnupiravir in non-hospitalised adults and children aged 12 years and older with COVID-19 who are symptomatic and showing no evidence of clinical recovery in accordance with the criteria set out in this document. The options are:

  • First-line: nirmatrelvir plus ritonavir (as per the published NICE MTA)
  • Second-line: sotrovimab (as per the published NICE MTA)
  • Third-line: remdesivir (where supply is available)
  • Fourth-line: molnupiravir