Minimising Clostridioides difficile and Gram-negative Bloodstream Infections

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The NHS Standard Contract includes quality requirements for NHS trusts and NHS foundation trusts to minimise rates of both Clostridioides difficile (C. difficile) and of Gram-negative bloodstream infections to threshold levels set by NHS England. The thresholds for each trust, together with the methodology used to identify these, are set out in this document.

Summary

Version 4. Updated April 2026.

If you require access to the Excel tables contained within the NHS Standard Contract 2026/27: Minimising Clostridioides difficile and Gram-negative bloodstream infections, Version 4, please contact england.improveipc@nhs.net.