As the programmes take effect, the city will increasingly act as a coordinated London Health Innovation Zone (HIZ). The London HIZ will be based around an orchestration model, aligning existing system partners (including the NHS, local government, the Mayor of London, academia and industry) and assets to deliver the six London-wide programmes.

As part of this work, the London HIZ will also:

• Agree and publish shared London priorities for health and care innovation via a London Problem Book;
• Align funding, data, research and expertise to reduce fragmentation and duplication; enable London to act as a single health and care economy, leveraging collective scale;
• Accelerate adoption of proven innovations using London‑wide levers;
• Focus on innovation across key sectors: (i) pharmaceutical, (ii) medical devices, (iii) digital health, and (iv) operational productivity improvements. Private sector partners will play a critical role in shaping priorities & delivering the strategy;
• Pool expertise from health, academia, public health, local government, and communities into three “adoption hubs” to test, adapt, evaluate and accredit new pathways based on priorities from the London Problem Book. These hubs will be tasked to take priority innovations from real-world testing to adoption decisions and be coordinated by the Health Innovation Network (South London),  Imperial College Health Partners and UCLPartners.

The London Health Innovation Zone (HIZ), alongside the implementation of the London Life Sciences Strategy, marks a step-change in how our city brings innovation to life. Building on recent progress, we are moving decisively towards a more coordinated, system-wide approach -one which enables the NHS, industry, academia and the third sector to work together with greater purpose, pace and scale. By aligning novel funding, procurement and regulatory mechanisms, we are creating the conditions to accelerate adoption and deliver impact for Londoners far more rapidly than ever before.

This ambition is grounded in the strengths that already define our city. London brings together world-class talent, a globally significant research base, a uniquely integrated health system, and access to deep pools of investment. Through programmes such as OneLondon, we are also building one of the most powerful health data assets in the world, providing an unparalleled platform to understand population health, generate evidence, and drive continuous improvement.

Over the past decades, London’s life sciences sector has delivered remarkable advances—often in the absence of full-system coordination. The opportunity ahead is to unlock far greater impact by connecting these strengths, focusing them on our most pressing challenges, and enabling innovations to scale across the whole city rather than remaining localised.

Looking ahead, we see a London where innovators choose to develop their products in London and proven innovations move rapidly from pilot to widespread adoption; where investment, data and expertise are aligned around shared priorities; and where our life sciences sector plays a central role not only in improving outcomes, but in tackling inequalities and supporting inclusive economic growth.

London has already demonstrated what is possible through individual excellence and that working in collaboration magnifies this impact. By working together deliberately, systematically and at scale we can transform that potential into a step-change in health, prosperity and opportunity for all Londoners and for the life-sciences sector in London.