Healthcare associated infection (HCAI) compendium of guidance and resources

This compendium collates current guidance, guidelines, policy and legislation, and other resources related to infection prevention and control (IPC) into a single source. This compendium will be routinely updated (at least quarterly) to incorporate new or updated resources and remove resources that have been withdrawn.

Disclaimer: No responsibility will be taken for any omissions to or the content of the compendium. Any questions regarding any of the guidance documents should be directed to the appropriate organisation.

Version 21, 8 April 2026

Updates to the previous version are highlighted in yellow

1. Antimicrobial resistance and prescribing

8 May 2024

3 April 2017

  • Antimicrobial Resistance: resource handbook – GOV.UK (www.gov.uk): Identifies current national policy, guidance and supporting materials in relation to the infection prevention and control of healthcare associated infections (HCAI) and antimicrobial stewardship in order to aid in the reduction of antimicrobial resistance | Identifies current national policy, guidance and supporting materials in relation to the infection prevention and control of healthcare associated infections (HCAI) and antimicrobial stewardship in order to aid in the reduction of antimicrobial resistance.

18 May 2022

22 April 2016

23 January 2024

  • Overview | Neonatal infection | Quality standards | NICE: This quality standard covers preventing infection in newborn babies, treating pregnant women whose babies are at risk of infection, and treating newborn babies with suspected or confirmed infection. It includes when to give antibiotics to prevent and treat neonatal infection. It describes high-quality care in priority areas for improvement – National Institute for Heath and Care Excellence

2020

March 2018

November 2016

June 2025

  • AMR local indicators: AMR local indicators are publicly available data intended to raise awareness of antibiotic prescribing, AMR, HCAI, IPC and AMS; and to facilitate the development of local action plans | UK Healthy Security Agency – Office for Health Improvement and Disparities.

2. General IPC

17 April 2014

  • Overview | Infection prevention and control | Quality standards | NICE: This quality standard covers preventing and controlling infection in adults, young people and children receiving healthcare in primary, community and secondary care settings. It includes preventing healthcare-associated infections that develop because of treatment or from being in a healthcare setting. It describes high-quality care in priority areas for improvement. National Institute for Heath and Care Excellence.

1 Nov 2016

18 Nov 2019

  • Minimum requirements for infection prevention and control programmes: The purpose of this document is to present and promote the minimum requirements for IPC programmes at the national and health care facility level, identified by expert consensus according to available evidence and in the context of the WHO core components. World Health Organization.

28 Apr 2022

13 Dec 2022

25 May 2022

  • Global Strategy on Infection Prevention and Control: Draft resolution proposed by Bosnia and Herzegovina, Botswana, Colombia, Jordan, Kenya, Kingdom of Saudi Arabia, Lebanon, Norway, Oman, Philippines, Qatar, United Arab Emirates, United States of America and Vanuatu. World Health Organization.

20 Jun 2022

20 Jun 2022

13 Dec 2022

13 June 2022

  • National Infection Prevention and Control Manual: Addendum for Infection Prevention and Control within Neonatal Settings (NNU): This addendum provides additional guidance to chapters 1,2 and 3 of the NIPCM (Scotland) specific to NNUs including, placement of neonates/assessment of infection risk, management of healthcare infection incidents, outbreaks and data exceedances, and personal care of neonates. National Services Scotland.

16 July 2025

  • NHS England Winter planning and preparedness: Ensuring robust winter preparedness is a key priority for the NHS England Transformation Executive. This resource sets out NHS England’s approach to winter planning for 2025.

3. Aseptic technique

4 June 2021

  • Understanding Aseptic Technique | Royal College of Nursing: Aseptic technique is recognised as an essential component of all infection prevention programmes but terminology used to define it varies. This publication is an RCN investigation into clinical views to guide the practice of aseptic technique. BD have funded this report. BD has had no influence on, or involvement in its content. Royal College of Nursing.

1 January 2014

4. Preventing infections associated with vascular access devices

1 January 2014

5. Preventing urinary tract infections

23 November 2018

12 December 2024

31 October 2018

27 July 2022

27 July 2022

11 June 2015

  • Overview | Urinary tract infections in adults | Quality standards | NICE: This quality standard covers diagnosing and managing urinary tract infection in adults (aged 16 and over), including adults using urinary catheters. It includes assessment, antibiotic treatment and referral for specialist assessment. It describes high-quality care in priority areas for improvement. National Institute for Heath and Care Excellence.

18 September 2013

07 July 2025

1 January 2014

No date

  • NHS England » Urinary catheter tools: The urinary catheter tools have been developed collaboratively with national experts to support providers in delivering consistent evidence based catheter care. The use of the tools needs to be supported by strong leadership and education. NHS England.

No date

  • DRIPP Urinary Catheter Resources: A urinary catheter quick reference guide and summary of evidence. Improving Device Related Infection Prevention Practice (DRIPP).

6. Surgical site infection

19 August 2020

  • Overview | Surgical site infections: prevention and treatment | Guidance | NICE: This guideline covers preventing and treating surgical site infections in adults, young people and children who are having a surgical procedure involving a cut through the skin. It focuses on methods used before, during and after surgery to minimise the risk of infection. National Institute for Heath and Care Excellence.

1 December 2018

7. Respiratory infections (including pneumonia)

2 September 2025

  • Pneumonia: diagnosis and management: This guideline covers diagnosing, assessing, and treating community-acquired and hospital-acquired pneumonia, including bacterial pneumonia secondary to COVID-19, in babies over 1 month (corrected gestational age), children, young people and adults. It aims to optimise antibiotic use and reduce antibiotic resistance. National Institute for Health and Care Excellence

16 September 2019

31 October 2023

  • Overview | Pneumonia in adults: diagnosis and management | Guidance | NICE: This guideline was developed before the COVID-19 pandemic. It covers diagnosing and managing pneumonia in adults who do not have COVID-19. It aims to improve accurate assessment and diagnosis of pneumonia to help guide antibiotic prescribing and ensure that people receive the right treatment. National Institute for Health and Care Excellence.

4 December 2015

  • National guidance for the management of children in hospital with viral respiratory tract infections (2025): These recommendations on the management of children in hospital with viral respiratory tract infections in hospital settings are for clinicians to support planning in partnership with local infection prevention control teams. While some recommendations describe organisational structures in England, services in the devolved nations are encouraged to adopt them to fit local models. This guidance is supported by the Infection Prevention Society.
    Royal College of Paediatrics and Child Health

11 January 2023

  • XBB.1.5 Rapid risk assessment: Rapid risk assessment by the WHO’s Technical Advisory Group on Virus Evolution (TAG-VE) of the public health risk associated with this variant. World Health Organization.

8. Health technical memoranda/Health building notes

26 January 2024

  • NHS England » (HTM 00) Building engineering in the health sector: HTM 00 provides guidance on the design, installation and operation of a healthcare facility from an engineering and environmental perspective. HTM 00 is not intended to cover every possible scenario, for example where a patient is receiving treatment in their own home. This 2014 edition supersedes all previous versions of HTM 00. Department for Health and Social Care.

26 January 2024

  • NHS England » (HTM 03-01) Specialised ventilation for healthcare buildings: These documents give comprehensive advice and guidance on the legal requirements, design implications, maintenance and operation of specialised ventilation in healthcare premises providing acute care. In other types of healthcare a risk assessment of the nature of the treatment being delivered, condition of the patients and intensity of use needs to be undertaken by those responsible for the facility in order to determine the extent to which this guidance will be applicable. Health Technical Memorandum 03-01 (2021) supersedes all previous versions of Health Technical Memorandum 03-01 – ‘Specialised ventilation in healthcare premises’ (2007). It also supersedes HTM 2025 (1994) and DV4 (1983). Department for Health and Social Care.

27 August 2024

  • NHS England » (HTM 04-01) Safe water in healthcare premises: This Health Technical Memorandum (HTM) gives guidance on the legal requirements, design applications, maintenance and operation of hot and cold water supply, storage and distribution systems in all types of healthcare premises. The guidance is for: healthcare management water safety groups design engineers estate managers operations managers contractors supply chain businesses It also provides advice and guidance on the control and management of the risk posed by Legionella, Pseudomonas aeruginosa and other water borne pathogens within a healthcare setting. Department for Health and Social Care.

26 January 2024

  • NHS England » (HTM 07-01) Management and disposal of healthcare waste: HTM 07-01 details the environmental benefits of the safe management and disposal of healthcare waste, It also presents opportunities for cost savings, safer working practices and reducing carbon emissions related to the management of waste. Department of Health and Social Care.

26 January 2024

26 January 2024

26 January 2024

26 January 2024

  • NHS England » (HTM 01-06) Management and decontamination of flexible endoscopes: Health Technical Memorandum (HTM) 01-06 provides information on the management and decontamination of flexible endoscopes. The guidance consists of 5 parts: policy and management; design and installation; operational management; validation and verification (including storage/drying cabinets); testing methods. Department for Health and Social Care.

30 January 2024

  • NHS England » (HBN 00-09) Infection control in the built environment: This building note details each stage of a project, from initial concept through to post-project evaluation, in relation to infection control. A building’s design can help infection prevention and control by providing an environment that is easy to clean and maintain. It is important that these features are designed into a project from the beginning. Department for Health and Social Care.

31 January 2024

26 January 2024

  • NHS England » (HTM 07-01) Management and disposal of healthcare waste: HTM 07-01 details the environmental benefits of the safe management and disposal of healthcare waste, It also presents opportunities for cost savings, safer working practices and reducing carbon emissions related to the management of waste. Department of Health and Social Care.

13 November 2023

  • Health Building Note 16-01: Facilities for mortuaries, including body stores and post-mortem services: This publication has been produced for use by NHS Trusts and Foundation Trusts. However, it has been designed to be useful for other organisations involved in the operation, planning or use of mortuary and post-mortem facilities in England, for either joint/shared service or individual organisation use. This publication replaces HBN 20 – ‘Facilities for mortuary and post-mortem room services’ (2005). NHS England.

9. Hand hygiene

15 January 2009

  • WHO guidelines on hand hygiene in health care: The WHO Guidelines on Hand Hygiene in Health Care provide health-care workers (HCWs), hospital administrators and health authorities with a thorough review of evidence on hand hygiene in health care and specific recommendations to improve practices and reduce transmission of pathogenic microorganisms to patients and HCWs. The present Guidelines are intended to be implemented in any situation in which health care is delivered either to a patient or to a specific group in a population. Therefore, this concept applies to all settings where health care is permanently or occasionally performed, such as home care by birth attendants. World Health Organization.

5 May 2012

9 February 2009

No date

  • Skin at work. Work-related skin disease (eg dermatitis) can affect people in a wide range of occupations. This site shows how the APC approach (avoid, protect, check) can reduce the chances of suffering painful and sometimes debilitating skin conditions. World Health Organization.

10. Personal protective equipment

No date

No date

  • Respiratory protective equipment (RPE) (hse.gov.uk). This website provides information and tools to help employers select and manage the use of respiratory protective equipment (RPE) in the workplace. The information is applicable to disposable and reusable masks, breathing apparatus and powered respirators. Health and Safety Executive.

2013

  • Respiratory protective equipment at work: A practical guide (hse.gov.uk). This fourth edition provides essential guidance on why respiratory protective equipment (RPE) should be used, what the law says and how to select RPE that is adequate and suitable. It also includes a useful dos and don’ts list for the management and supervision of RPE use. The guidance is aimed principally at employers and the self-employed who wear, or are responsible for workers who wear, RPE. It will also be useful for health and safety specialists, manufacturers and suppliers of RPE. It has been prepared in consultation with industry and updates the 2005 edition. Health and Safety Executive.

No date

15 October 2025

  • Guidelines on hand hygiene in community settings (World Health Organization). These guidelines are concerned with the practice of hand hygiene to protect community health outcomes, in particular, the reduction of diarrhoeal diseases and acute respiratory infections. They are particularly relevant to long-term development contexts, complementing existing recommendations on hand hygiene in acute humanitarian response settings available through the Sphere standards for promotion of water, sanitation and hygiene. The guidelines are intended for use in a routine health system context to improve population health, and also during health emergencies, as part of broader response strategies.

October 2025

11. Safe management of patient care equipment and the care environment

1 July 2023

28 January 2021

1 December 2013

1 August 2013

22 January 2020

17 May 2024

5 September 2016

5 July 2016

25 February 2021

31 October 2014

11 April 2014

March 2016

June 2022

1 June 2022

  • Automated room decontamination: report of a Healthcare Infection Society Working Party – Journal of Hospital Infection. Aims to provide useful, generic information that will help healthcare professionals make a well-informed choice if they are intending to buy or rent/lease the automated technology. The aim is to provide guidance on the types of device available, the various active chemicals (where relevant), the biocidal mechanism underpinning the technology, suggested information to be sought from the supplier before purchase, and general precautions recommended for the safe and effective use of the equipment. Healthcare Infection Society.

1 January 2019

June 2020

18 November 2022

2 May 2025

  • Infection prevention and control: incubators on neonatal units. This document sets out to highlight and reinforce general infection prevention and control (IPC) principles to be used in combination with local guidance and manufacturer’s instructions when decontaminating and handling incubators in neonatal units during and after patient use. UK Health Security Agency.

24 January 2022

30 January 2025

6 February 2025

  • National Standards of Healthcare Cleanliness 2025. The National standards of healthcare cleanliness 2025 encompass all cleaning tasks throughout the NHS regardless of which department is responsible for it. They are based around being easy to use; freedom within a framework; fit for the future; efficacy of the cleaning process; cleanliness which provides assurance; and transparency of results. NHS England.

2 October 2023

2 October 2023

2 June 2025

30 January 2025

  • The Principles of Medical Device Decontamination: This document provides an accessible introduction to the essential principles, processes, and standards involved in the decontamination of reusable medical devices. Designed as a single, easy‑to‑navigate source, it uses minimal text supported by images, tables, and flow charts to help healthcare practitioners understand core concepts and signpost them to more detailed guidance. Decontamination Professional Experts Communications Forum (DPECF)

12. IPC during care of the deceased

July 2018

13. Safe management of linen

28 March 2023

  • NHS England » Uniforms and workwear: guidance for NHS employers: This publication supports the specific requirements of the Health and Social Care Act 2008 Code of Practice relating to uniform and workwear policies, and the need to ensure that they support effective hand hygiene. Advise on the washing of uniforms is included. NHS England.

14. Occupational safety including the prevention of sharps injuries

2013

No date

  • Blood-borne viruses (BBV) – Blood-borne viruses (BBV): This website gives employees and employers detailed guidance on; how to comply with the law; how to assess and ways to reduce the risks of workplace exposure to blood-borne viruses; how to manage incidences of exposure. Health and Safety Executive.

30 March 2016

11 June 2025

15 January 2025

15. High consequence infectious diseases

15 January 2026

13 January 2026

  • Viral haemorrhagic fever: ACDP algorithm and guidance on management of patients – GOV.UK: This document provides guidance on the risk assessment and management of patients in the United Kingdom in whom infection with a viral haemorrhagic fever (VHF) should be considered or is confirmed. This guidance aims to eliminate or minimise the risk of transmission to healthcare workers and others coming into contact with an infected patient or their samples. Advisory Committee on Dangerous Pathogens (ACDP).

23 October 2024

16. Management of outbreaks

8 September 2025

6 June 2008

  • Pandemic Flu – Workplace Guidance: This guidance is intended to inform planning for a pandemic form of influenza that causes severe symptoms in a large proportion of those infected. Health and Safety Executive.

No date

17. Healthcare associated infection surveillance and reporting

4 January 2021

1 August 2017

20 September 2022

4 October 2017

12 July 2018

12 July 2018

22 January 2020

24 June 2025

  • Surgical site infection (SSI): guidance, data and analysis: UK Health Security Agency helps hospitals record incidents of surgical site infection (SSI), to help improve surgical practice and prevent further infections. UK Health Security Agency.

1 August 2016

18. Risk assessment and the hierarchy of controls

22 January 2024

22 January 2024

September 2022

  • Dental framework – Supporting guidance for primary and community care dental settings: This dental framework has been designed to support practices in identifying hazards and risks with guidance on measures that should be maintained as we move to new, improved, and safer ways of working. In balancing risks appropriately, the framework provides a consistent handrail applicable to the generic dental practice environment. NHS England.

2013

8 April 2025

  • National infection prevention and control board assurance framework: The Board Assurance Framework (BAF) provides assurance to trust boards, that organisational compliance has been systematically reviewed by assessing the measures taken in line with the National Infection Prevention and Control Manual (NIPCM) and the Code of Practice (COP). NHS England.

October 2024 

  • Isolation prioritisation tool: The isolation prioritisation tool is intended to provide a systematic framework that can be used by healthcare staff in organisations to assist in the prioritisation of isolation rooms for infection prevention and control. NHS England.

19. IPC in the ambulance service

31 October 2025

April 2022

April 2022

20. IPC in prisons, education, childcare and social care settings

21 March 2026

27 March 2026

1 March 2024

31 May 2022:

18 February 2013

No date

15 May 2025

  • Infection prevention and control in care homes: This site contains questions and prompts used by CQC inspectors to look at how well staff and people living in care homes are protected by infection prevention and control (IPC). Care Quality Commission

05 January 2026

21. Sustainability

24 July 2022

  • Delivering a ‘Net Zero’ National Health Service: This report provides a detailed account of the NHS’ modelling and analytics underpinning the latest NHS carbon footprint, trajectories to net zero and the interventions required to achieve that ambition. It lays out the direction, scale and pace of change. It describes an iterative and adaptive approach, which will periodically review progress and aims to increase the level of ambition over time. NHS England.

No date

  • Green Surgery – Reducing the environmental impact of surgical care: The Green Surgery report provides initiatives and recommendations to reduce the adverse impact of surgical care on the environment, based upon evidence synthesis and case studies. It also considers barriers and facilitators to implementation. Key contributors of emissions in the operating theatre include products (in particular single-use items), energy consumption, and anaesthetic gases (many of which are powerful greenhouse gases). UK Health Alliance on Climate Change.

22. Resources for appropriate glove use

 

2018

  • Glove awareness | Campaigns | Royal College of Nursing: The RCN Glove Awareness campaign encourages nursing staff to use disposable gloves only when clinically necessary and to prioritise proper hand hygiene instead of routine glove use where no infection risk exists. Royal College of Nursing

May 2018

  • RCN-guidance-Tools-of-the-Trade.pdf: A professional clinical guidance document for health care workers (including nurses and assistants) that explains how and when gloves should be used, how inappropriate glove use affects IPC and staff skin health, and how to prevent work related contact dermatitis. Royal College of Nursing

No date

  • Greener NHS: Gloves off campaign: Clear list of when gloves are not required (vital signs, feeding, admin tasks, pushing equipment, dispensing medicines, observations, documentation, meal trays). Education on risks of dermatitis and reduced hand hygiene when gloves are overused. Lancashire and South Cumbria Integrated Care Board

August 2022

  • NHS England – North West » Case study – Gloves-Off: Reduce unnecessary glove use, improve sustainability, and support better hand hygiene practices through the gloves off campaign which included patient engagement (such as posters) and collaborating with procurement, audits and regular campaign meetings. Manchester University NHS Foundation Trust

2023

No date

  • Gloves off: West Yorkshire Health and Care Partnership: A regional awareness initiative across West Yorkshire health and care services aimed at reducing unnecessary use of disposable gloves and promoting effective hand hygiene when appropriate instead of routine glove use. West Yorkshire Health & Care Partnerships

12 October 2023

  • Using gloves appropriately in healthcare: A new animation for their ‘Gloves off’ campaign highlighting the critical importance of hand hygiene and proper glove usage in healthcare – complementing the getting back to basics theme. Infection Prevention Society

No date

  • Gloves off in critical care: A practical resource designed to help healthcare teams in intensive care settings reduce unnecessary use of disposable gloves and improve hand hygiene practices. Intensive Care Society

September 2023

October 2024

  • Reducing the Unnecessary Use of Non-Sterile Gloves: Aims to reduce unnecessary use of non-sterile gloves across NHS Scotland – in operating theatres, wards, outpatients and other clinical settings. The initiative responds to sustained high glove usage since the COVID-19 pandemic and the associated infection control, environmental, and financial impacts. National Green Theatres Programme (part of NHS Scotland’s Centre for Sustainable Delivery)

Publication reference: PR00206