Specialised immunology and allergy services

This Lead and Inform Clinical Reference Group (CRG) covers specialised treatment of certain immunological and allergic conditions.


This clinical reference group covers:

  • Immunological conditions including:
    • primary immunodeficiencies
    • autoimmune and autoinflammatory disease where there is associated immunodeficiency
    • complex autoimmune and vasculitic conditions
    • autoinflammatory syndromes
  • Allergic conditions including severe, complex and/or rare sub-groups.


  • Dr Claire Bethune, National Specialty Advisor (Chair)
  • Dr Susana Marinho, Clinical Member
  • Professor Anthony Williams, Clinical Member
  • Dr Ariharan Anantharachagan, Clinical Member
  • Dr Stephanie Kayode, Clinical Member
  • Daniel Clarke, Clinical Member
  • Dr Helen Baxendale, Clinical Member
  • Dr Catherine Elliott, Clinical Member
  • Dr Matthew Buckland, Affiliate Member
  • Dorothea Grosse Kreul, Affiliate Member
  • Zoe Hamilton, Lead Commissioner
  • Sue Dimmock, Patient & Public Voice
  • Jess Hobart, Patient & Public Voice


A key part of the CRG’s work is the delivery of the ‘products’ of commissioning. These are the tools used by the 10 Hub Commissioning Teams to contract services on an annual basis.

Service specifications

Service specifications are important in clearly defining the standards of care expected from organisations funded by NHS England to provide specialised care. The specifications have been developed by specialised clinicians, commissioners, expert patients and public health representatives to describe both core and developmental service standards. Core standards are those that all funded providers should be able to demonstrate, with developmental standards being those which may require further changes in practice over time to provide excellence in the field.

The following service specifications fall within the scope of this CRG:


A commissioning policy is a document that defines access to a service for a particular group of patients. A NICE Technology Appraisal Guideline on the same topic will replace, or be incorporated into, a commissioning policy as appropriate. These are important documents that are developed to ensure consistency in access to treatments nationwide.

The following policies fall within the scope of this CRG.


Not routinely commissioned:

Get involved

If you are interested in the work of the immunology and allergy CRG or its NPoC, you can register as a stakeholder.

For details on our latest consultations please visit the NHS England consultation hub.

Get in contact

For any questions or queries relating to the work of the immunology and allergy CRG or its NPoC, please contact: england.npoc-bloodandinfection@nhs.net