Chemotherapy dose standardisation
National dose banding tables
The Chemotherapy Dose Standardisation initiative has been developed by NHS England’s Medicine Optimisation and Chemotherapy CRGs. NHS England is supporting the standardisation of chemotherapy doses which will deliver benefits for patients, Hospital Trusts and achieve improved value from our investment in chemotherapy services.
Historically when patients received chemotherapy intravenously their dose would be based on a combination of their height and weight and would mean that pharmacies would waste any medicine left over from vials containing fixed doses. A number of hospitals have already moved to a system of dose banding where a range of doses are delivered to closely match to vial size. This means there is reduced waste and as these doses tend to be ready made it also reduces the waiting time for patients within the chemotherapy unit.
The National Dose Banding Tables are to be used by Hospital Trust Pharmacy Teams to ensure a standard approach to dose banding of Chemotherapy across all Hospital Trusts. The initiative is initially focussed on 19 commonly used drugs. This will help the NHS achieve improved value through the ability to purchase standard off the shelf products.
- National Dose Banding Table – 2mgmL – v6
- National Dose Banding Table – 25mgmL – v2
- National Dose Banding Table – 80mgmL – v2
- National Dose Banding Table – Avelumab 20mgmL – v2
- National Dose Banding Table – Azacitidine 25mgmL – v3
- National Dose Banding Table – Bevacizumab 25mgmL – v2
- National Dose Banding Table – Brentuximab Vedotin 5mgmL – v3
- National Dose Banding Table – Capecitabine v1
- National Dose Banding Table – Carfilzomib 2mgmL v6
- National Dose Banding Table – Cladribine SC Litak 2mgml v1
- National Dose Banding Table – Cetuximab 5mgmL – v4
- National Dose Banding Table – Clofarabine 1mgmL – v2
- National Dose Banding Table – Daratumumab 20mgmL v1
- National Dose Banding Table – Doxorubicin Lip (Caelyx) 2mgmL – v3
- National Dose Banding Table – Durvalumab 50mgml v1
- National Dose Banding Table – Eribulin 0.44mgmL v3
- National Dose Banding Table – Irinotecan 20mgml v.1
- National Dose Banding Table – Inotuzumab ozogamicin 0.25mgml v1
- National Dose Banding Table – Ipilimumab 5mgmL v1
- National Dose Banding Table – Isatuximab 20mg/mL v1
- National Dose Banding Table – Mesna 100mgmL – v5
- National Dose Banding Table – Methotrexate HD 100mgmL – v2
- National Dose Banding Table – Nivolumab 10mgmL – v2
- National Dose Banding Table – Paclitaxel Albumin 5mgmL – v1
- National Dose Banding Table – Panitumumab 20mgmL – v1
- National Dose Banding Table – Pembrolizumab 25mgmL – v2
- National Dose Banding Table – Pemetrexed 25mgmL v3
- National Dose Banding Table – Polatuzumab vedotin 20mg mL v1
- National Dose Banding Table – Rituximab 10mgmL – v4
- National Dose Banding Table – Topotecan 1mgmL – v3
- National Dose Banding Table – Trastuzumab IV 21mgmL – v2
- National Dose Banding Table – Trastuzumab emtansine 20mgmL – v2
- National Dose Banding Table- Trastuzumab deruxtecan 20mg/mL v1
- National Dose Banding Table – Temozolomide PO v2
- National Dose Banding Table – Vinflunine 25mgmL – v2
Dose banded chemotherapy standardised product specifications
NHS England has published the first set of product specifications to support the production and supply of ready-made chemotherapy medicines. This supports the chemotherapy dose standardisation programme and the utilisation of standard chemotherapy doses. The specifications will be utilised by procurement teams to ensure the NHS will purchase standard, readymade products across the NHS in England. The scheme provides benefits for patients with ready to use products and drives safety throughout the system by standardising the products that are used. In addition, it provides benefits to Trusts and commissioners in reducing waste.
- Dose Banded Chemotherapy Standardised Product Specifications – Background | User Guide | Stakeholder Testing Briefing | Appendix 1 | Appendix 2
- Amsacrine 500ml infusion bags
- Arsenic Trioxide 100ml infusion bags
- Azacitidine pre-filled syringes
- Bendamustine 500ml infusion bags
- Bevacizumab 100ml infusion bags
- Bortezomib pre-filled syringes
- Cabazitaxel 250ml infusion bags
- Carboplatin 500ml infusion bags
- Carfilzomib 100ml infusion bags
- Cetuximab 500ml infusion bags
- Cisplatin 250ml to 1000ml infusion bags
- Cladribine 500ml infusion bags and Cladribine pre-filled syringes
- Clofarabine 100ml infusion bags
- Cyclophosphamide infusion bags and Cyclophosphamide pre-filled syringes
- Cytarabine 250ml infusion bags and Cytarabine pre-filled syringes
- Dacarbazine 1000ml infusion bags
- Daunorubicin 250ml infusion bags and Daunorubicin pre-filled syringes
- Docetaxel 250ml and 500ml infusion bags
- Doxorubicin Liposomal 250ml and 500ml infusion
- Doxorubicin pre-filled syringes
- Epirubicin pre-filled syringes
- Eribulin Base 50ml infusion bags
- Etoposide 250ml and 500ml and 1000ml infusion
- Fludarabine 100ml infusion bags and Fludarabine pre-filled syringes
- Fluorouracil 1000ml infusion bags, Fluorouracil in Elastomeric Infusion Devices and Fluorouracil pre-filled syringes
- Gemcitabine 250ml infusion bags
- General Product Specification Requirements
- Idarubicin pre-filled syringes and Idarubicin 100ml infusion bags
- Ifosfamide and Mesna 1000ml infusion bags
- Ifosfamide 1000ml infusion bags
- Irinotecan 250ml infusion bags
- Mesna 1000ml infusion bags
- Methotrexate 500ml infusion bags and Methotrexate pre-filled syringe
- Mitomycin pre-filled syringes
- Mitoxantrone 100ml infusion bags
- Nivolumab 50ml and 100ml infusion bags
- Oxaliplatin 250ml and 500ml infusion bags
- Paclitaxel Albumin infusion bags
- Paclitaxel 250ml and 500ml infusion bags
- Panitumumab 100ml infusion bags
- Pentostatin pre-filled syringes
- Pembrolizumab 50ml and 100ml infusion bags
- Pemetrexed disodium 100ml infusion bags
- Rituximab 250ml and 500ml infusion bags
- Streptozocin 250ml infusion bags
- Thiotepa 250ml and 500ml and 1000ml infusion
- Topotecan 50ml, 100ml, 250ml and 500ml infusion
- Trastuzumab 250ml infusion bags
- Vinblastine 50ml infusion bags
- Vincristine 50ml infusion bags
- Vinflunine 100ml infusion bags
- Vinorelbine 50ml infusion bags