National dose banding tables

The systemic anti‑cancer therapies dose standardisation initiative was developed by NHS England’s former Medicines Optimisation and Chemotherapy Clinical Reference Groups. It aims to standardise SACT dosing to deliver benefits for patients and hospital trusts.

Dose banding involves rounding doses to align closely with available vial sizes. This approach reduces waste and, as doses are often prepared in advance, can also shorten waiting times for patients receiving SACT.

The national dose banding tables are intended for use by pharmacy teams in all NHS hospital trusts in England to ensure a consistent approach across all organisations.

NHS England and NICE consider dose standardisation to represent the standard of care for adult patients treated within the NHS in England. Accordingly, where patients are receiving standard‑of‑care treatment as part of a clinical trial, dosing should be aligned to standardised (banded) doses.

• How to use the dose banding tables
• National dose banding table – drug list
• National dose banding table – 1mgmL – v5
• National dose banding table – 1mgmL multi-syringe – v3
• National dose banding table – 2mgmL – v7
• National dose banding table – 2mgmL multi-syringe – v2
• National dose banding table – 2.5mgmL – v3
• National dose banding table – 5mgmL – v3
• National dose banding table – 6mgmL
• National dose banding table – 10mgmL – v6
• National dose banding table – 20mgmL Multi-Syringe – v3
• National dose banding table – 20mgmL – v7
• National dose banding table – 25mgmL – v2
• National dose banding table – 25mgmL Multi-Syringe – v5
• National dose banding table – 38mgmL
• National dose banding table – 50mgmL
• National dose banding table – 80mgmL – v2
• National dose banding table – 100mgmL – v4
• National dose banding table – azacitidine 25mgmL – v3
• National dose banding table – belantamab mafodotin 50mgmL
• National dose banding table – bendamustine 45mgmgmL v1
• National dose banding table – bevacizumab 25mgmL – v2
• National dose banding table – bleomycin 3000iumL
• National dose banding table – brentuximab Vedotin 5mgmL – v3
• National dose banding table – capecitabine 
• National dose banding table – carfilzomib 2mgmL v7
• National dose banding table – cladribine SC Litak 2mgml v1
• National dose banding table – cetuximab 5mgmL – v4
• National dose banding table – clofarabine 1mgmL – v2
• National dose banding table – daratumumab 20mgmL v1
• National dose banding table – doxorubicin Lip (Caelyx) 2mgmL – v3
• National dose banding table – durvalumab 50mgml v1
• National dose banding table – enfortumab vedotin 10mg/mL
• National dose banding table – eribulin 0.44mgmL v3
• National dose banding table – irinotecan 20mgml v.1
• National dose banding table – inotuzumab ozogamicin 0.25mgml v1
• National dose banding table – ipilimumab 5mgmL v1
• National dose banding table – isatuximab 20mg/mL v1
• National dose banding table – loncastuximab tesirine v1
• National dose banding table – mesna 100mgmL – v5
• National dose banding table – methotrexate HD 100mgmL – v2
• National dose banding table – mirvetuximab soravtansine 5mgmL – v1
• National dose banding table – mogamulizumab 4mgmL – v1
• National dose banding table – nivolumab 10mgmL – v3
• National dose banding table – paclitaxel Albumin 5mgmL – v1
• National dose banding table – panitumumab 20mgmL – v1
• National dose banding table – pembrolizumab 25mgmL – v3
• National dose banding table – pemetrexed 25mgmL v3
• National dose banding table – polatuzumab vedotin 20mg mL v1
• National dose banding table – raltitrexed 0.5mgmL
• National dose banding table – rituximab 10mgmL – v4
• National dose banding table – sacituzumab govitecan 10mg/mL
• National dose banding table – serplulimab 10mgmL
• National dose banding table – siltuximab v1
• National dose banding table – talquetamab 2mg/mL
• National dose banding table – talquetamab 40mg/mL
• National dose banding table – teclistamab 90mgmL
• National dose banding table – teclistamab 10mgmL
• National dose banding table – tisotumab vedotin 10mgmL 
• National dose banding table – topotecan 1mgmL – v3
• National dose banding table – trastuzumab IV 21mgmL – v2
• National dose banding table – trastuzumab emtansine 20mgmL – v2
• National dose banding table – trastuzumab deruxtecan 20mg/mL v1
• National dose banding table –  trifluridine tipiracil
• National dose banding table – temozolomide PO v2
• National dose banding table – vinflunine 25mgmL – v2
• National dose banding table – vyxeos liposomal 2.2mg5mgmL v1
• National dose banding table – zanidatamab 50mgmL